منابع مشابه
Holding it together: chromatin in the Archaea.
Recently, several advances have been made in the understanding of the form and function of archaeal chromatin. Remarkable parallels can be drawn between the structure and modification of chromatin components in the archaeal and the eukaryotic domains of life. Indeed, it now appears that key components of the hugely complex eukaryotic chromatin regulatory machinery were established before the di...
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متن کاملThe Falling Slinky
Consider a slinky that is held at one end while the rest of it is allowed to hang freely. If the slinky is released, then as it falls due to gravity it also shrinks in extent due to the contracting force in the slinky itself. A few years ago it was discovered that the net effect of these two changes exactly counteract each other at the bottom extent of the slinky and therefore the bottom of the...
متن کاملSLINKY: Static Linking Reloaded
Static linking has many advantages over dynamic linking. It is simple to understand, implement, and use. It ensures that an executable is self-contained and does not depend on a particular set of libraries during execution. As a consequence, the user executes exactly the same executable image as was tested by the developer, diminishing the risk that the user’s environment will affect correct be...
متن کاملChromatin is an ancient innovation conserved between Archaea and Eukarya
The eukaryotic nucleosome is the fundamental unit of chromatin, comprising a protein octamer that wraps ∼147 bp of DNA and has essential roles in DNA compaction, replication and gene expression. Nucleosomes and chromatin have historically been considered to be unique to eukaryotes, yet studies of select archaea have identified homologs of histone proteins that assemble into tetrameric nucleosom...
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ژورنال
عنوان ژورنال: Science
سال: 2021
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.372.6541.477-b